Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCNX All Species: 21.82
Human Site: Y2096 Identified Species: 40
UniProt: Q96RV3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RV3 NP_055797.2 2341 258676 Y2096 L H P P V T S Y P P T L G T S
Chimpanzee Pan troglodytes XP_510039 2300 254005 Y2055 L H P P V T S Y P P T L G T S
Rhesus Macaque Macaca mulatta XP_001084081 2342 258864 Y2097 L H P P V T S Y P P T L G T S
Dog Lupus familis XP_537501 2332 257280 Y2087 L H P P V T S Y P P A L G T S
Cat Felis silvestris
Mouse Mus musculus Q9QYC1 2344 258128 Y2099 L H P P T T S Y P P T L G T S
Rat Rattus norvegicus NP_001163818 2343 257924 Y2098 L H P P T T S Y P P T L G T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423893 2312 255194 H2053 Q H P P V A P H P G A H P T A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923995 2285 252748 Q2047 L G T S Q S S Q S V Q S G L V
Tiger Blowfish Takifugu rubipres Q98UF7 1703 191329 G1467 D A G G L S C G T S Q S S Q S
Fruit Fly Dros. melanogaster P18490 3433 367590 G2851 V A A P G T A G S T G G E S G
Honey Bee Apis mellifera XP_624687 2092 236172 L1856 I I G G P L S L G V I K S N V
Nematode Worm Caenorhab. elegans NP_492790 1634 183268 P1398 A P V T L T T P P Q T E R E R
Sea Urchin Strong. purpuratus XP_001195494 2799 311472 Q2153 Q Q Q Q P Q Q Q G G S E S G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 98.7 94.4 N.A. 90.9 91.1 N.A. N.A. 84.9 N.A. 66.7 54.4 29.4 38.7 27.7 35.5
Protein Similarity: 100 98.1 99.4 96.4 N.A. 95.5 95.3 N.A. N.A. 90.8 N.A. 77.7 63 42.9 55.5 41.8 49.2
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 40 N.A. 20 6.6 13.3 6.6 20 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 53.3 N.A. 26.6 20 33.3 13.3 33.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 8 0 0 8 8 0 0 0 16 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 16 8 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 16 16 8 0 0 16 16 16 8 8 54 8 8 % G
% His: 0 54 0 0 0 0 0 8 0 0 0 8 0 0 0 % H
% Ile: 8 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % K
% Leu: 54 0 0 0 16 8 0 8 0 0 0 47 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 8 54 62 16 0 8 8 62 47 0 0 8 0 0 % P
% Gln: 16 8 8 8 8 8 8 16 0 8 16 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % R
% Ser: 0 0 0 8 0 16 62 0 16 8 8 16 24 8 62 % S
% Thr: 0 0 8 8 16 62 8 0 8 8 47 0 0 54 0 % T
% Val: 8 0 8 0 39 0 0 0 0 16 0 0 0 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 47 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _